I most definitely do care about the civilian casualties in the middle east. But like I mentioned before, this is war, and there are always civilian casualties in war, especially urban war, where (iirc) most of the civilian casualties are occurring. The problem is not that there are civilian casualties (though that is definitely a problem) but how many were avoidable. There are, the way I see it, four different categories. Those who were killed by our troops directly (ie, targeted intentionally or unintentionally), those killed by our troops indirectly (ie, collateral damage from missile strikes, etc), those killed by enemy troops indirectly (ie, IEDs, mines, etc), and those killed by enemy troops directly (I would include the woman killed in bin Laden's capture in this category, regardless of who fired the shot that killed her). Only the first category do our people have any direct control over, and the second category they have a range of control over, the extent of which would depend on the specific circumstances. I don't know the numbers, but I would be willing to bet that the vast majority of civilian casualties have been in the third category or the result of firefights in urban areas. Take Kabul for example. At one time a point of heavy fighting, and still today, I believe. That city has a population density of ~17,267 people per square mile. 40% greater than that of London. How likely do you think civilian casualties would be if a major battle were to break out in the middle of London?
I'm not saying that civilian casualties do not matter. What I am saying is that it is foolish to think that a war could be waged with zero civilian casualties. Especially when the enemy combatants hide in civilian, residential areas. Our two countries are blessed in that we have not had a war conducted on our soil for at least the last ~150 years, so at first glance we compare it to ourselves and think "What!? How dare they let civilians get caught in a firefight!" But imagine an active firefight in a crowded neighborhood in downtown London, and how many people would die just because they happened to be in the wrong place at the wrong time.
You mentioned missile strikes in residential areas. Since I seem to remember reading about something similar, how about this scenario. Intelligence is received that an enemy leader is occupying a specific house but will be gone and back in hiding by morning; let's say, 8 hours. Leaving this enemy leader free would likely result in the deaths of thousands but the nearest troops are 10 hours away. However, aircraft could be directed to the location and a surgical warhead could be used to destroy the house in question with little damage to any surrounding buildings. Would you make the strike even knowing that civilian casualties were a possibility?
What I'm trying to say is; war is messy and uncertain. Horrible things happen in war. But I think even with the horrible things that have been done in this war, we have done more good than harm.